Friday, 20 January 2012

Man pleads no contest to stalking Halle Berry (AP)

LOS ANGELES ? A man accused of scaling the fence of Halle Berry's house will remain in jail after pleading no contest to stalking the Oscar-winning actress.

Deputy District Attorney Wendy Segall says Richard A. Franco was sentenced to serve 386 days in county jail Thursday, but he has already served half the term.

The 28-year-old was also placed on five years' probation, a year of psychological counseling and ordered to stay away from the actress for the next decade.

Franco was arrested outside Berry's home in July after repeatedly coming onto her property. In one instance, the actress stated in a sworn declaration that Franco attempted to enter her kitchen, but she was able to lock the door before he got inside.

A burglary charge filed against Franco was dropped.

Source: http://us.rd.yahoo.com/dailynews/rss/celebrity/*http%3A//news.yahoo.com/s/ap/20120119/ap_en_mo/us_people_halle_berry

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Thursday, 19 January 2012

Spain Targets Regions' Debt

MADRID?Spain's government on Tuesday moved forward with its plans to institute new controls on spending by its powerful regions, an essential part of its effort to slash one of Europe's largest budget deficits.

Budget Minister Crist?bal Montoro said the country's 17 regions have agreed to surrender some autonomy and submit to new legislation that will set penalties for failure to comply with budget targets, two weeks after the new government of Prime Minister Mariano Rajoy announced a much-higher-than-expected 2011 budget deficit of 8% of gross domestic product.

The agreement represents a big reversal for Spanish regions, which have a long ...

MADRID?Spain's government on Tuesday moved forward with its plans to institute new controls on spending by its powerful regions, an essential part of its effort to slash one of Europe's largest budget deficits.

Budget Minister Crist?bal Montoro said the country's 17 regions have agreed to surrender some autonomy and submit to new legislation that will set penalties for failure to comply with budget targets, two weeks after the new government of Prime Minister Mariano Rajoy announced a much-higher-than-expected 2011 budget deficit of 8% of gross domestic product.

The agreement represents a big reversal for Spanish regions, which have a long ...

Source: http://online.wsj.com/article/SB10001424052970203735304577167091842144700.html?mod=rss_europe_whats_news

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Natural enzyme provides potential new approach for treating graft-vs.-host disease

ScienceDaily (Jan. 17, 2012) ? A natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease, a common and deadly side effect of lifesaving bone marrow transplants.

Researchers from the University of Michigan Comprehensive Cancer Center looked at the drug alpha-1-antitrypsin, which is approved by the U.S. Food and Drug Administration for use in people who have a genetic mutation that makes them deficient in a certain enzyme. This drug has been used in many of these patients over extended periods of time and is known to cause minimal side effects.

More important, there are no known reports of increased susceptibility to infections. This is key for people with graft-vs.-host disease, where existing treatment options tend to suppress the immune system, putting patients at risk of infection. Graft-vs.-host disease is a major complication of bone marrow transplants using marrow from a donor, called an allogeneic transplant. This often-deadly side effect is what makes the procedure so risky.

"If we can get graft-vs.-host disease under control, we can more effectively use allogeneic bone marrow transplant to treat people with leukemia and lymphoma as well as other blood disorders. It would be a curative therapy for people who otherwise have no hope," says senior study author Pavan Reddy, M.D., associate professor of hematology/oncology at the U-M Medical School.

In this study, which appears in the Proceedings of the National Academy of Sciences, researchers used alpha-1-antitrypsin in mice that received allogeneic bone marrow transplants. The drug significantly reduced mortality from graft-vs.-host disease, compared to control mice who did not receive the drug.

In addition, alpha-1-antitrypsin reduced the number of inflammatory cells called T Effector cells that are known to be present in graft-vs.-host disease. It also increased the number of T-regulatory cells, which immunologists believe play a positive role in immune responses.

"It's likely the balance between the T-regulatory cells and the T Effector cells that leads to graft-vs.-host disease. Alpha-1-antitrypsin appears to have tipped that balance favorably," says lead study author Isao Tawara, M.D., Ph.D., a research investigator at the U-M Medical School.

The U-M researchers collaborated on this work with researchers from the University of Colorado and from Ben Gurion University of the Negev in Israel. The researchers are beginning to discuss a possible clinical trial using alpha-1-antitrypsin in post-transplant patients with graft-vs.-host disease for whom conventional therapies are no longer working.

Additional authors include Yaping Sun, Tomomi Toubai, Rebecca Evers and Evelyn Nieves, all from U-M; Eli C. Lewis, from Ben-Gurion University of the Negev in Israel; Tania Azam and Charles A. Dinarello, from the University of Colorado.

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The above story is reprinted from materials provided by University of Michigan Health System.

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Journal Reference:

  1. I. Tawara, Y. Sun, E. C. Lewis, T. Toubai, R. Evers, E. Nieves, T. Azam, C. A. Dinarello, P. Reddy. Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation. Proceedings of the National Academy of Sciences, 2011; 109 (2): 564 DOI: 10.1073/pnas.1117665109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2012/01/120117144224.htm

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Wednesday, 18 January 2012

Wikipedia to shut for 24 hours over US anti-piracy laws

Jacob Aron, technology reporter

rexfeatures_1260595d.jpg(Image: Roland Kemp/Rex Features)

Wikipedia, the sixth-most visited website on the internet, is planning a major shutdown to protest against the Stop Online Piracy Act (SOPA) and PROTECT IP Act (PIPA), two proposed laws aimed at halting online piracy that critics say could seriously harm the internet.

From 5am GMT tomorrow, the English language version of the online encyclopaedia will be replaced by a single black page asking visitors to contact US politicians and express their opposition to the proposed laws. The decision to shutdown the site was reached in typical Wikipedia fashion, with users discussing the pros and cons before eventually agreeing to go ahead with the protest.

The community rushed to reach a consensus so that the protest could coincide with other website blackouts, including social news site Reddit and news blog Boing Boing, set for 18 January, the same day as a planned SOPA hearing in the US Congress.

That hearing has now been postponed following criticism of the legislation from the White House, but Wikipedia founder Jimmy Wales says the protest will still go ahead. "Unclear that SOPA is really dead, but messaging will target the reality on the ground on Wednesday," he said on Twitter, later adding that PIPA, which is still due to be debated by the US Senate, remains "a live threat".

Not all Wikipedians support the protest, however. Some have complained about the speed at which the decision was reached, while others questioned the need for an international blackout to protest US legislation.

Other websites wanting to join the protest can now use an app created by CloudFlare, the web security service previously used by LulzSec to protect its website from attacks. CloudFlare users can activate the Stop Censorship app to automatically black out words longer than five characters and ask visitors to protest the new laws.


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Source: http://feeds.newscientist.com/c/749/f/10897/s/1be505cd/l/0L0Snewscientist0N0Cblogs0Conepercent0C20A120C0A10Cwikipedia0Eto0Eprotest0Eus0Eanti0Ep0Bhtml0DDCMP0FOTC0Erss0Gnsref0Fonline0Enews/story01.htm

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Windows Phone: Skype app 'coming soon'

Windows Phones will feature a Skype app "soon," according to a Skype executive. But Windows Phone owners may have to wait several months for the feature.

Microsoft?s acquisition of Skype promised to be a marriage made in an integration heaven ? especially for Windows Phones owners ? but so far it?s been all talk and no action.

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A Skype for Windows Phone application, however, will soon make its debut, Skype vice president of products Rick Osterloh asserted in a recent interview taped at the Consumer Electronics Show in Vegas.

?We?re ? working on a Windows Phone product that will be coming out soon,? he said.

When Microsoft purchased the video-conferencing company for $8.5 billion in June 2011 (the deal closed in October), it talked up an unrivaled Windows Phone Skype offering that would include deep integration between the voice over IP service and its mobile operating system. But the merger still has Windows Phone owners waiting for platform integration, let alone a basic application on par with what?s already offered on iPhone, Android and BlackBerry.

That wait is likely to continue. The first Windows Phone product, according to The Verge, could be released as soon as the Mobile World Congress in February, but it won?t be the much-ballyhooed operating system-wide offering originally touted by the companies. Windows Phone owners may have to wait for this rich Skype integration until the Apollo software release, which, according to a leaked roadmap, won?t happen until the fourth quarter of 2012.

?We understand, from our own sources, that the initial release of Skype will not feature deep Windows Phone integration, and that Microsoft is planning this for ?Apollo? and beyond,? The Verge is reporting. ?Microsoft?s first Windows Phone Skype application will largely be seen as an interim release until Windows Phone ?Apollo? is made available.?

But Microsoft and Skype would like you to know that integrations are coming ? eventually. ?We?re working with a lot of different Microsoft product groups to create direct integrations,? Osterloh said. ?Right now, we?re working on Windows Phone, we?ll be working on Windows 8, Xbox, Lync. So a whole range of different Microsoft users will get access to Skype and have a great experience.?

Skype, Osterloh said, now has more than 200 million monthly users.

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Source: http://rss.csmonitor.com/~r/feeds/csm/~3/n3w6wJv8ntE/Windows-Phone-Skype-app-coming-soon

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Tuesday, 17 January 2012

More, Faster Weight Loss Seen With Gastric Bypass Than Banding (HealthDay)

MONDAY, Jan. 16 (HealthDay News) -- Gastric bypass surgery results in faster and longer-lasting weight loss than does gastric banding, according to a new study by Swiss investigators.

A gastric bypass operation called Roux-en-Y involves reducing stomach size with staples and connecting the smaller "pouch" directly to the small intestine. It is irreversible.

Gastric banding, as its name implies, involves placing a band around part of the stomach to reduce its size. This procedure is reversible, the researchers noted.

"Both gastric banding and gastric bypass are currently performed for morbid obesity," said lead researcher Dr. Michel Suter, chief surgeon at Chablais Hospital in Aigle.

"Bypass is more effective in terms of directs results such as weight loss, but a bit more dangerous immediately than banding," he said.

However, banding often leads to long-term complications requiring some sort of major re-operation, Suter said.

"In addition, many bands are not going to stay in place for much more than 10 years; hence, banding is unlikely to be the only weight-loss procedure the patient will be submitted to," he said. "Patients should make a choice knowing this, and decide whether they accept a slightly higher early risk to improve their results, or if they want the least invasive procedure, but then accept a high risk of further surgery at a later time."

The report was published in the Jan. 16 online edition of the Archives of Surgery.

For the study, Suter's team followed for six years 442 patients who had either gastric bypass surgery or banding.

Although there were more early surgical complications among those who had Roux-en-Y surgery, these patients lost more weight faster than those who had gastric banding, the researchers found.

After bypass surgery, about 17 percent of the patients had complications, compared with more than 5 percent of those who underwent banding, the researchers noted.

But at six years there were more problems with gastric banding, including about 48 percent who had weight gain or the procedure reversed, compared with about 12 percent who had bypass surgery, the study found.

Gastric banding was associated with more long-term complications (more than 42 percent versus 19 percent) and more new procedures than bypass surgery (about 27 percent vs. 13 percent).

Cholesterol levels among those who had gastric bypass surgery were consistently lower than among those who had gastric banding, who saw no change over time, the researchers add.

This finding implies that blood sugar levels were also lower among those who underwent gastric bypass surgery, the study authors said.

Suter is concerned that many patients are only offered banding and not told of its drawbacks.

"There is, in the United States, an extensive campaign promoting gastric banding as 'the solution' for obesity, which is far from being true," he said.

It can result in significant weight loss, but it remains a surgical procedure, and is certainly associated with significant risks, both in the short and long term, Suter said.

"Patients must be informed that surgery alone is not sufficient to achieve significant weight loss, and they must be instructed about other things they have to do such as changing their eating and lifestyle habits," he said.

In addition, Suter said, "Patients calling or referred for gastric banding must be informed about the other available procedures for morbid obesity, and not offered band only, as is the case in several places."

Depending on the actual operation, either procedure costs between $10,000 and $20,000 plus follow-up costs, and insurance coverage is very inconsistent, according to Dr. Edward Livingston, who serves as the Dr. Lee Hudson-Robert R. Penn Chair in Surgery at the University of Texas Southwestern Medical Center, in Dallas.

Hospital stay for bypass is usually two days, and banding usually one day, but this can vary depending on surgeon, hospital and complications.

Dr. Jacques Himpens, from the European School of Laparoscopic Surgery at Saint Pierre University Hospital in Brussels and author of an accompanying journal editorial, is less concerned with a particular procedure than with the specific surgeon.

"Not all surgeons can do bypasses," he said. "Maybe they don't have the skills or the experience, but in any case it's not the best option because they are not up to it," he said. "That's the case for many surgeons."

In addition, it is not clear what the long-term results of a bypass are, because there is evidence that although a bypass "cures" diabetes, it does come back after time, Himpens said.

"The bypass is a very good procedure, but not everyone can do it and we have to be very careful and watch what the long-term effects of the procedure are," he said.

Also, while a gastric bypass causes changes in metabolism, banding does not, Himpens said.

"But the good thing is that it is reversible. When you take out the band, no harm has been done and you can still do another procedure if you need to," he said.

However, among patients who receive bands, only 40 percent retain them after 10 years, either because of complications or the desire to have it removed, Himpens said.

More information

For more on gastric bypass procedures, visit the U.S. National Library of Medicine.

Source: http://us.rd.yahoo.com/dailynews/rss/weightloss/*http%3A//news.yahoo.com/s/hsn/20120116/hl_hsn/morefasterweightlossseenwithgastricbypassthanbanding

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Monday, 16 January 2012

Iran warns Gulf Arabs on oil (AP)

CAIRO ? Iran warned Gulf Arab oil producers against boosting production to offset any potential drop in Tehran's crude exports in the event of an embargo affecting its oil sales, the latest salvo in the dispute between the West and the Islamic Republic over its nuclear program.

The comments by Iran's OPEC governor, published Sunday, came as Saudi Arabia's oil minister was quoted the same day denying that his country's earlier pledges to boost output as needed to meet global demand was linked to a potential siphoning of Iranian crude from the market because of sanctions.

World oil markets have been jolted over concerns that Iran may choke off the vital Strait of Hormuz in retaliation for sanctions hampering its ability to sell its oil. Saudi Arabia and other key Gulf Arab producers have recently said they are ready to provide stable and secure supplies of oil.

The U.S. recently imposed sanctions targeting Iran's central bank and, by extension, refiners' ability to buy and pay for crude. The European Union is also weighing an embargo on Iranian oil, while Japan, one of Iran's top Asian customers, has pledged to buy less crude from the country.

Mohammad Ali Khatibi, Iran's OPEC governor, was quoted Sunday by the pro-reform Shargh newspaper as saying that attempts by Gulf nations to replace Iran's output with their own would make them an "accomplice in further events."

"These acts will not be considered friendly," Khatibi said, adding that if the Arab producers "apply prudence and announce that they will not participate in replacing oil, then adventurist countries will not show interest," in the embargo.

The embargo concerns are linked to Iran's nuclear program. The West maintains Iran is enriching uranium for weapons purposes while Tehran says its program is for purely peaceful purposes such as generating electricity.

Saudi Arabia, the world's largest oil producer and a close U.S. ally, had said that it was ready to raise its output to accommodate global market needs. The country is the only member of the 12-nation Organization of the Petroleum Exporting Countries that has significant spare capacity, currently estimated at roughly more than 2 million barrels per day.

With concerns building amid the standoff between Iran and the West over Tehran's nuclear program, a string of Asian and Western officials have visited Saudi Arabia over the past week. While offering assurances that it could meet a shortfall in supply through its spare capacity, Saudi officials have also been careful to say that it was an internal matter if nations chose to abide by any sanctions.

Oil Minister Ali Al-Naimi appeared to try to further clarify the country's position in comments published Sunday in the daily Al-Ektisadiyah newspaper.

"We never said that Saudi Arabia is trying to compensate for Iranian oil in the case that sanctions (are enacted)," Al-Naimi was quoted as saying. "We said that we are prepared to meet the increase in global demand as a result of any circumstances."

The kingdom has a production capacity of 12.5 million barrels and is believed to be producing slightly over 9 million to 9.5 million barrels per day.

Iran's warning introduces a new layer of complication to an issue that has the potential for broad regional and global fallout.

"If the regional countries ... say no to what is harmful to the security of the region, then nothing will definitely happen," he said. But if the security of oil traffic in the Strait of Hormuz is violated, "all will be lost," he said.

"If these countries make a mistake and give the green light, this will be a historic green light," Khatibi said.

Saudi Arabia, the Arab world's largest economy, is widely seen as the main counterweight to Iran in the region. Any attempt by Iran to close the Strait of Hormuz, through which a sixth of the world's oil flows, would also affect the export abilities of the major Gulf producers, including Saudi Arabia, Iraq, the United Arab Emirates, Kuwait and Qatar.

While momentum appears to be building for the sanctions by the West, China, another major buyer of Iranian oil, has come out against the measures.

Chinese Premier Wen Jiabao was in Saudi Arabia on Saturday for meeting with officials in which the two countries "pledged to work together to further expand all-around exchanges and cooperation," according to China's Xinhua news agency

Wen said the two sides "should expand trade of crude oil and natural gas and energy-related cooperation as to deepen their energy partnership," Xinhua reported.

During the visit, Saudi state-owned oil giant Aramco and Chinese refiner Sinopec finalized an agreement to develop a 400,000 barrel per day joint venture refinery in the Red Sea city of Yanbu. The deal is just one between China and Gulf producers as the Asian powerhouse reaches out across the world to secure energy supplies for its booming economy.

___

Associated Press writer Nasser Karimi in Tehran contributed.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20120115/ap_on_bi_ge/ml_mideast_oil

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